HISTORY:
Earlier known as Oscela, Oscella, Oscella dei Leponzi, Ossolo, Ossola Lepontiorum, and Domo d'Ossola (because it is in the Ossola valley), was the chief town of the Lepontii when the Roman Empire conquered the region in 12 BC.
During the second World War Domodossola was part of an uprising against the Germans, whereby the valley of Ossola declared itself a republic and broke away from Facist Italy. The rebellion was crushed by German troops within a few months, but was an important symbol for anti-fascist movements within Italy until the end of the war.